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Credelio Plus - For Dogs - 25 - 48 lbs - Green (450/16.88mg) - 6 tablets

Credelio Plus - For Dogs - 25 - 48 lbs - Green (450/16.88mg) - 6 tablets
Part# 8230
Type Heartworm Preventatives
Brand Credelio Plus
Color / Dose Green (450/16.88mg)
Pack Size 6 Tablets
Pet For Dogs
Pet Weight 25 - 48 lbs
Expires 2026-May-1
User Rating   [Rate It!]

Unit Price $87.85

What is Credelio Plus?

Credelio Plus is a comprehensive, fast and convenient broad-spectrum treatment that is gentle on your dog but tough on parasites. The product offers effective worm control with milbemycine oxime, plus immediate and persistent tick and flea kill with lotilaner in just one tablet. It effectively kills fleas and ticks, prevents heartworm and flea tapeworm infections, plus kills adult and juvenile hookworms and roundworms along with adult whipworms. Credelio Plus is a tasty, beef-flavored monthly chewable tablet designed for use in puppies from the age of 8 weeks and more than 2.8 kg in bodyweight. The fast-acting formula starts killing fleas within 2 hours after administration and protects for a complete month.

Dosage and administration

Credelio Plus may be offered as a treat, or for fussy eaters it can be mixed with food or given as a tablet. It should be administered with or after the food once every month, preferably on the same date each month to make sure your dog is protected. Administer Credelio Plus to dogs in accordance with the weight of your dog to make the standard dose for lotilaner 20-41 mg/kg bodyweight and milbemycin oxime 0.75-1.53 mg/kg bodyweight is maintained.

Color Pet Weight (lb) Weight (kg) lotilaner (mg) Milbemycin Oxme (mg)
Yellow Ex Small Dogs 03 - 06 lbs 1.4 - 2.8 kg 56.25 mg 2.11 mg
Pink Small Dog 07 - 12 lbs 2.8 - 5.5 kg 112.5 mg 4.22 mg
Orange Medium Dogs 13 - 24 lbs 5.5 - 11 kg 225 mg 8.44 mg
Green Large Dogs 25 - 49 lbs 11 - 22 kg 450 mg 16.88 mg
blue Ex Large Dogs 49 - 99 lbs 22 - 45 kg 900 mg 33.75 mg

The majority of the dogs shall take the chewable from your hand, but if it isn't the case, hide the tablet in their food. Closely watch your dog to ensure the complete dose is consumed. In case, the dog does not take the complete tablet, re-dose at the earliest and then continue with monthly dosing.


  • Comprehensive protection in one dose
  • Treat flea infections in dogs
  • Kills flea eggs before they lay eggs
  • Treats and controls tick infestations including Paralysis ticks, Brown dog ticks and Bush ticks
  • Prevents heartworms
  • Kills adult and juvenile roundworms and hookworms
  • Prevents lungworm disease
  • Protects against adult whipworms
  • Prevents flea tapeworm infections
  • Highly palatable beef-flavour
  • Safe to use on puppies as young as 8 weeks of age and 2.8 kg in bodyweight
  • Fast-acting formula that starts killing fleas within 2 hours of administration
  • Provides month-round protection

How it works:

Credelio Plus consists of two active ingredients lotilaner and milbemycin oxime. Lotilaner actively kills fleas and ticks (including Paralysis ticks, Brown dog ticks and Bush ticks). The onset of killing fleas is within 2 hours; fleas are eliminated within 6-12 hours of administration and kills re-infesting fleas within 4-6 hours. The other ingredient milbemycin oxime is a known chemical component in Australia that targets deadly heartworms and gastrointestinal worms such as adult and juvenile roundworms and hookworms along with adult whipworms.

For dogs without flea and tick infestations, it works as an effective, long-lasting monthly topical preventative against fleas and ticks - just apply once a month.


The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. Use with caution in dogs with a history of seizures. Credelio is only for oral use in dogs. See Credelio label for complete safety information.

More Information:

Brand Name: Credelio Plus

Generic Name: Lotilaner and Milbemycin oxime

Credelio (Plus) is a chewable tablet that is used to treat flea infestations and treat and control tick infestations. This tasty beef-flavored chew kills fleas and 4 types of ticks: lone star tick, American dog tick, black-legged tick, and brown dog tick for a full month. Credelio is for dogs and puppies 8 weeks of age or older, weighing 4.4 lbs.

What should I discuss with my veterinarian before giving Credelio to my pet:
Tell your veterinarian if your pet is breeding, pregnant, or lactating. The safe use of Credelio in breeding, pregnant, or lactating dogs hasn't been evaluated. Tell your veterinarian if your pet has a history of seizures.

How should this medication be given:
Give Credelio orally once a month with food or within 30 minutes after feeding. Give the appropriate dosage based on your dog's weight. Credelio can begin at any time of the year and can continue year round without interruption.

What happens if I miss a dose:
Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose the pet:
If an overdose is suspected, contact your veterinarian.

What should I avoid while giving Credelio:
Avoid giving Credelio if your pet is breeding, pregnant, or lactating or has a history of seizures.

What are the possible side effects of Credelio:
Potential side effects of Credelio can include weight loss, elevated blood urea nitrogen (BUN), polyuria (excesssive urination), and diarrhea.

What other drugs will affect Credelio:
There are no known contraindications for the use of Credelio. Consult with your veterinarian if your pet is taking any other supplements or medications.

Where can I get more information:
Your pharmacist has additional information about Credelio written for health professionals that you may read.

Manufacturer: Elanco Animal Health

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